This study of utilization of 2 combined minipill preparations by 295 women over 12-18 months is intended to aid the general practitioner in prescribing an easily tolerated oral contraceptive. 152 patients were given Minidril (21 pills containing 30 mcg Ethinyl Estradiol (EE) and 150 mcg of levonorgestrel (LNG)), while 143 were given Adepal (7 pills containing 30 mcg EE and 150 mcg LNG and 14 containing 40 mcg EE and 200 mcg LNG). 2/3 receiving either prescription were between 20-30 years. 56% of Minidril and 50% of Adepal users had no children, 15% of Minidril and 20% of Adepal users had 1 child, and 17% of Minidril and 16% of Adepal users had a history of prior induced abortion. Minidril and Adepal respectively were prescribed in 51 and 32 cases as the first OC, after abortion in 22 and 12 cases, and after side effects with higher dose combined pills in 33 and 94 cases. Minidril was prescribed following use of Adepal in 39 cases, and Minidril and Adepal were prescribed following use of Stediril in 7 and 5 cases respectively. Adepal is useful in cases of weight gain, migraines, lipid intolerance, recurring candida infection, breakthrough bleeding, benign breast disease, and occasionally for frigidity. No pregnancies occurred with either pill, and tolerance was excellent. 3 secondary effects encountered in about 375 woman-years of Adepal use required discontinuation: 1 case of rapid increase in ovarian size, 1 case of hypertriglyceridemia, and 1 case of persistent breast pain, which disappeared after cessation of treatment. Breast discomfort in 12 cases disappeared after several months' use.