AimTo evaluate the variability of the measurements obtained with the Ocular Response Analyzer (ORA), particularly for the corneal hysteresis (CH), corneal resistance factor (CRF) and the corneal-compensated intraocular pressure (IOPcc).Material and MethodsBoth eyes of 30 healthy volunteers were prospectively measured with the ORA, including ametropia. The standard deviation (SD) and coefficient of variation (CoV) were calculated according to the mean values. The difference between the mean values of eight repeated measurements and the mean values of five or less repeated sessions were illustrated in a diagram. The difference with the fellow eye was expressed in percentage.ResultsThe mean values and SD/CoV obtained after five measurements were 16.04 ± 1.81/ 0.11 for the IOPcc, 10.64 ± 1.04/ 0.10 for the CH, and 10.72 ± 0.87/ 0.08 for the CRF. The mean values of five repeated exams only differed by 2.05% CRF, 2.51% CH, and 3.19% IOPcc from the mean values of eight exams, where as two exams differed by 3.9% CRF and 7.1% IOPcc.DiscussionThe ORA is at present the only device capable of quantifying the CH and CRF. Our mean values conformed to the mean values of recent studies from other authors. Regarding to the clinical application of the ORA the variability of the results makes it difficult to analyze the complexity of the biomechanical, especially if modified by surgery or other pathologies.ConclusionWe obtained repeatable scores especially for the CRF followed by the CH and lower results for the IOPcc. The variability of the results should be compensated by increasing the number of measurements depending on the required parameter. Further studies and technical evolution will help to improve standard methods to quantify visco-elastic properties of the cornea.